Immunomonitoring Platform
Dr. Claire Conche
Aim
The immunomonitoring platform offers tools and methodologies to study immune responses.
We are here to support you in bringing your ideas to experimental data.
We are specialized in experiments for analysis and sorting of cells by flow cytometry. We have long-standing experience in scientific research in immunology and tumor biology. Our expertise includes flow cytometry panel design, sample preparation as well as tailoring in vivo, in vitro, and ex vivo assays.
We are scientists too and are eager to support you in your research.
Immunomonitoring Platform
Dr. Claire Conche
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[since 2023] Head of the Immunomonitoring Platform, HI-TRON Mainz
[2017 - 2023] Senior Postdoctoral Fellow in Cancer Immunotherapies at the Georg Speyer Haus Frankfurt am Main
[2010 - 2015] Postdoctoral Fellow on T cell biology at The Scripps Research Institute, USA.
[2005 - 2009] Ph.D. Student on TCR signalling at the Cochin Institute, France
HI-TRON Mainz DKFZ
Immunomonitoring Platform
Obere Zahlbacherstr. 63
Building 911
55131 Mainz
Team
Selected publications of C.Conche
- Conche C, Finkelmeier F, Pesic M, Nicolas AM, Bottger T W, Kennel K B, Denk D, Ceteci F, Mohs K, Engel E, Canli O, Dabiri Y, Peiffer KH, Zeuzem S, Salinas G, Longerich T, Yang H, Greten FR. Combining ferroptosis induction with MDSC blockade renders primary tumours and metastases in liver sensitive to immune checkpoint blockade. Gut. 2023;72(9):1774-1782
- Denk D, Petrocelli V, Conche, C, Drachsler M, Ziegler PK, Braun A, Kress A, Nicolas AM, Mohs K, Becker C, Neurath MF, Farin HF, Buchholz CJ, Andreux PA, Rinsch C, Greten FR. Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy. Immunity. 2022;55(11):2059-2073
- Westernberg L, Conche C, Huang YH, Rigaud S, Deng Y, Siegemund S, Mukherjee S, Nosaka L, Das J, Sauer K. Non-canonical antagonism of PI3K by the kinase Itpkb delays thymocyte β-selection and renders it Notch-dependent. eLife. 2016;5:e10786
- Siegemund S, Rigaud S, Conche C, Broaten B, Schaffer L, Westernberg L, Head SR, Sauer K. IP3 3-kinase B controls hematopoietic stem cell homeostasis and prevents lethal hematopoietic failure in mice. Blood. 2015;125:2786-2797
Platform News
03/2024: 01/2024: A new member joins the Immunomonitoring Platform: Metin Tahsin Yaldiz
12/2023: The Cytek Aurora, our new spectral flow cytometer arrived.
Gallery
Created with BioRender.com
Created with BioRender.com
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